Variant Prolactin Receptor in Agalactia and Hyperprolactinemia

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Detection of macroprolactin causing hyperprolactinemia in commercial assays for prolactin.

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Effects of metoclopramide-induced hyperprolactinemia on the prolactin receptor of murine endometrium.

OBJECTIVE To evaluate the effects of metoclopramide-induced hyperprolactinemia on the prolactin receptor of murine endometrium. DESIGN Experimental study using the RNA extraction to detect tissue prolactin receptor isoforms by reverse-transcriptase polymerase chain reaction (RT-PCR). SETTING University-based laboratory. ANIMAL(S) Seventy-two female swiss albino mice (Mus musculus), approx...

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Lymphocytic prolactin does not contribute to systemic lupus erythematosus hyperprolactinemia.

OBJECTIVES Lymphocytic prolactin (PRL) gene expression is detected in the majority of the immune cells and it is not known if this source contributes to hyperprolactinemia in systemic lupus erythematosus (SLE). We have therefore evaluated lymphocytic PRL secretion and gene expression in SLE and healthy controls. METHODS Thirty SLE patients (ACR criteria) and 10 controls were selected for the ...

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Prolactin Receptor Expression and Prolactin-mediated Effects in Adipose Tissue

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2018

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmoa1805171